For US residents age 18 and older

Prescribing Information | Patient Information | Important Safety Information

US Patients/Caregivers Toggle US Healthcare Professionals

ISEMBYLD (apitegromab-mstn) injection 150mg/3mL logo

PatientsToggle For Healthcare Professionals

Ready to talk
with your doctor?
Download this guide
Download guide pdf icon

Build a new way forward

Here’s what to expect when starting ISEMBYLD and how to get support throughout your treatment journey.

Ask your doctor whether ISEMBYLD is right for you

Choosing a treatment for SMA is a significant step. Talk to your doctor to see whether ISEMBYLD fits into your current plan, what the day-to-day experience is like, and what kind of results you may expect.

Choosing a treatment for SMA is a significant step. Talk to your doctor to see whether ISEMBYLD fits into your current plan, what the day-to-day experience is like, and what kind of results you may expect.

ISEMBYLD Doctor Discussion Guide

A little planning goes a long way

Need tips for talking to your care team? The Doctor Discussion Guide will help you lead the conversation and get the answers you need.

DOWNLOAD DISCUSSION GUIDE

Complete the enrollment form with your doctor

A completed enrollment form activates Scholar Rock Supports™, the patient support program that helps with navigating costs and copays, insurance, and more (see details below). Your designated Rx Onboarding and Care Coordinator (ROCC) will contact you directly once they have received your completed enrollment form.

A completed enrollment form activates Scholar Rock Supports™, the patient support program that helps with navigating costs and copays, insurance, and more (see details below). Your designated Rx Onboarding and Care Coordinator (ROCC) will contact you directly once they have received your completed enrollment form.

ISEMBYLD enrollment form

Get started now

Remember, both you and your prescribing healthcare provider must sign the form and submit it before support can begin.

Download enrollment form

Descargar formulario de inscripción

Start your
treatment

ISEMBYLD is given as an intravenous (IV) infusion every 4 weeks while on treatment, meaning that it is infused into a vein in the hand ​or arm. Based on eligibility, the infusion ​is administered by a healthcare professional with the flexibility of choosing between 3 locations.

Home, Hospital, and Infusion Center icons

ISEMBYLD is given as an intravenous (IV) infusion every 4 weeks while on treatment, meaning that it is infused into a vein in the hand ​or arm. Based on eligibility, the infusion ​is administered by a healthcare professional with the flexibility of choosing between 3 locations.

Home, Hospital, and Infusion Center icons
ISEMBYLD is given as a ~1-to 2-hour IV infusion every 4 weeks

Additional time may be required by your healthcare team for monitoring after the infusion.

Do not stop treatment with ISEMBYLD unless your healthcare provider tells you to.

Your healthcare provider will determine the amount of ISEMBYLD needed based on your current weight.

If you miss a dose of ISEMBYLD, either:

  • ISEMBYLD should be given (administered) as soon as possible and then restart the dosing schedule 4 weeks after the missed dose is given, or
  • the dose can be skipped and the next dose can be given as originally scheduled.

Curious about the treatment experience?

See what infusion day may look like.

ISEMBYLD Infusion day brochure

Get to know the infusion process

The Infusion Day Brochure can help you understand the basics and what you need to know before, during, and after each infusion.

DOWNLOAD INFUSION BROCHURE

Scholar Rock Supports logo

Support that meets you where you are

Scholar Rock Supports was built around the idea that no one should have to navigate treatment alone. Once enrolled, you’ll be supported by an experienced and dedicated team, including a ROCC (Rx Onboarding and Care Coordinator) who helps guide your experience and coordinates the right resources based on your needs—including education, insurance support, infusion logistics, and more.

Visit Scholar Rock Supports

Real Scholar
Rock Supports
dedicated team
members

Your ROCC can help with:

  • Navigating insurance
  • Understanding costs and copays
  • Discussing treatment expectations
  • Caregiver resources and guidance
  • Infusion day planning and support

Your coverage is worth fighting for

If your insurance does not approve ISEMBYLD at first, you’re not alone. Your doctor can ask your insurance company to review the decision. Talk to your ROCC for help, or use the sample letter below. The letter can help you explain how SMA affects your daily life and tell your story. You can give your letter to your doctor, who can include it when asking your insurance company to review the decision.

Download sample Letter of Appeal for patients and caregivers

New — Patient Brochure

Take ISEMBYLD information with you

Keep all the details handy. Download the ISEMBYLD Patient Brochure to save, print, or share this information whenever you need it.

New — Patient Brochure

DOWNLOAD PATIENT BROCHURE